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Mathew, Daniel

Assistant Professor of Reproductive Physiology

Dr. Daniel Mathew grew up on a family row crop and swine farm in North West Indiana. He and his father later owned and operated a small beef cow-calf operation in East Tennessee while Daniel pursued a bachelor’s degree in Animal Science from the University of Tennessee. There, Daniel became interested embryology and pursued a M.S. and later, Ph.D. in Reproductive Physiology from the Division of Animal Sciences at the University of Missouri. During his graduate program, Daniel investigated molecular signaling between the early embryo and uterus in swine. He then moved to Ireland where he received post-doctoral training in a bovine in vitro fertilization and embryo research laboratory at the University College Dublin.


Dr. Mathew’s research program aims to improve reproductive health and efficiency in large animal livestock. Using laboratory and on farm approaches, he investigates early embryonic development and basic reproductive process during gestation. His research interests include early embryonic mortality, embryo-uterine communication, embryo implantation and assisted reproductive technologies. He currently teaches the course Endocrinology and lectures in the course Reproductive Physiology in the Fall and Spring semesters, respectively. 


Select Publications

  1. Mathew D. J.*, J. M. Sánchez, C. Passaro, G. Charpigny, S. Behura, T. E. Spencer and P. Lonergan. Interferon tau-dependent and independent effects of the bovine conceptus on the endometrial transcriptome: effect of conceptus origin and sex. 2018. Biol Reprod.
  2. Geisert R. D., J. J. Whyte, A. E. Meyer, D. J. Mathew, M. R. Juarez, M. C. Lucy, R. S. Prather and T. E. Spencer. 2017. Review: Rapid conceptus elongation in the pig: An interleukin 1 beta 2 and estrogen regulated phenomena. Mol Reprod Dev 84(9):760-774. doi: 10.1002/mrd.22813.
  3. Mathew D. J.*, M. C. Lucy and R. D. Geisert. 2016. Review: Interleukins, interferons and establishment of pregnancy in pigs. Reprod doi: 10.1530/REP-16-0047.
  4. Mathew D. J.*, E. M. Newsom, J. M. Guyton, C. K. Tuggle, R. D. Geisert and M. C. Lucy. 2015. Activation of the transcription factor nuclear factor-kappa B (NFKB) in uterine luminal epithelial cells by interleukin-1 beta 2 (IL1B2): a novel interleukin-1 expressed by the elongating pig conceptus. Biol Reprod 92(4): 107 1-13
  5. Lucy M. C., R. C. Escalante, D. H. Keisler, W. R. Lamberson and D. J. Mathew. 2013. Short communication: Glucose infusion into early postpartum cows defines an upper physiological set point for blood glucose and causes rapid and reversible changes in blood hormones and metabolites. J Dairy Sci 96(9): 5762-5768.
  6. Mathew D. J.*, E. M. Sellner, J. C. Green, C. S. Okamura, L. L. Anderson, M. C. Lucy, and R. D. Geisert. 2011. Uterine progesterone receptor expression, conceptus development and ovarian function in pigs treated with RU 486 during early pregnancy. Biol Reprod 84(1): 130-139.
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